Porter was substituted early in the second half on Sunday at the Aviva Stadium after appearing to roll his ankle in a game the hosts eventually won 57-6.

Earlier this week it was hoped that Porter, who made 43 appearances for his country, and center Robbie Henshaw could return for Ireland’s next matches against England and Scotland.

Loosehead Porter had returned to light training, although further analysis showed he would not be able to regain full fitness by the end of the Championship, and he returned to Leinster for further treatment.

A statement from Irish Rugby said: “Following analysis of his injured ankle, Andrew Porter has been ruled out of the remainder of our Guinness Six Nations campaign.

“He has returned to Leinster Rugby and his medical treatment will be managed by the Leinster medical team.”

📋 𝐒𝐪𝐮𝐚𝐝 𝐔𝐩𝐝𝐚𝐭𝐞.

Following analysis of his injured ankle, Andrew Porter has been ruled out of the rest of our #GuinnessSixNations countryside.

He returned to @LeinsterRugby and his medical treatment will be managed by the Leinster medical team.#TeamOfUs pic.twitter.com/oQ2u8AaVoE

— Irish Rugby (@IrishRugby) March 3, 2022

Dave Kilcoyne came off the bench to replace Porter four days ago and is a likely candidate to replace the prop in Andy Farrell’s squad.

Experienced Cian Healy and Finlay Bealham are other potential options to cover the No.1 shirt.

Ireland sit second in the Guinness Six Nations, having started the league with a convincing first-round win over Wales before losing to leaders France at the Stade de France in the second round.

Farrell’s side will then be in action at Twickenham against England next weekend before wrapping up their campaign in Dublin against Scotland on Super Saturday.

The team held an open training session for the first time since 2020 this morning, with fans allowed into the Aviva Stadium to watch the team prepare for their final two matches alongside the Under-20s of Richie Murphy, who will play their second Grand Slam in four. years.